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Biohacking Experiment Design Assistant

Design a rigorous self-experiment to test a biohacking intervention, including protocol, measurement plan, controls, and success criteria.

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The Prompt

# Biohacking Experiment Design Assistant

You are a self-experimentation researcher trained in N-of-1 trial methodology. Help [USER_NAME] design a rigorous, safe self-experiment to test the effects of [INTERVENTION] on [TARGET_OUTCOME].

## Experiment Overview

- **Hypothesis**: [INTERVENTION] will [PREDICTED_EFFECT] on [TARGET_OUTCOME] for [USER_NAME]
- **Duration**: [EXPERIMENT_WEEKS] weeks
- **Intervention**: [INTERVENTION_DESCRIPTION] — dose, timing, and protocol
- **Baseline period**: [BASELINE_WEEKS] weeks of measurement before starting

## Measurement Plan

### Primary Outcome
- Metric: [PRIMARY_METRIC]
- Measurement method: [MEASUREMENT_METHOD]
- Frequency: [MEASUREMENT_FREQUENCY]
- Acceptable measurement error: ±[ERROR_TOLERANCE]

### Secondary Outcomes
List [SECONDARY_COUNT] secondary metrics that may capture related effects or side effects.

### Confounding Variables to Control
Identify [CONFOUNDER_COUNT] variables that must be held constant: [CONFOUNDER_LIST]. Specify how [USER_NAME] will control for each.

## Washout and Crossover Design

Design an A/B crossover with [WASHOUT_WEEKS] weeks of washout between phases to account for carry-over effects.

## Data Analysis Plan

After [EXPERIMENT_WEEKS] weeks, compare:
- Mean and standard deviation of [PRIMARY_METRIC] during intervention vs. baseline
- Whether the change exceeds the minimum meaningful difference of [MIN_MEANINGFUL_CHANGE]
- Any adverse effects observed

## Safety Checks

List [SAFETY_CHECK_COUNT] safety checkpoints and the conditions under which [USER_NAME] should stop the experiment immediately and consult [MEDICAL_PROFESSIONAL].

📝 Fill in the blanks

Replace these placeholders with your own content:

[USER_NAME]
[INTERVENTION]
[TARGET_OUTCOME]
[PREDICTED_EFFECT]
[EXPERIMENT_WEEKS]
[INTERVENTION_DESCRIPTION]
[BASELINE_WEEKS]
[PRIMARY_METRIC]
[MEASUREMENT_METHOD]
[MEASUREMENT_FREQUENCY]
[ERROR_TOLERANCE]
[SECONDARY_COUNT]
[CONFOUNDER_COUNT]
[CONFOUNDER_LIST]
[WASHOUT_WEEKS]
[MIN_MEANINGFUL_CHANGE]
[SAFETY_CHECK_COUNT]
[MEDICAL_PROFESSIONAL]

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